Edward Jenner, an English country doctor, gave the first vaccination against smallpox.
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Smallpox is officially declared eradicated.
A medical paper on smallpox was published in Boston, making it the first medical publication in American history.
Janet Parker became the last person to die of smallpox in Birmingham, United Kingdom.
Dr. Zabdiel Boylston of Harvard University gave the first smallpox inoculations in Boston following America's biggest outbreak.
Smallpox eradication was certified.