Edward Jenner, an English country doctor, gave the first vaccination against smallpox.
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A medical paper on smallpox was published in Boston, making it the first medical publication in American history.
Janet Parker became the last person to die of smallpox in Birmingham, United Kingdom.
Smallpox is officially declared eradicated.
Smallpox eradication was certified.
Dr. Zabdiel Boylston of Harvard University gave the first smallpox inoculations in Boston following America's biggest outbreak.