A medical paper on smallpox was published in Boston, making it the first medical publication in American history.
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Dr. Zabdiel Boylston of Harvard University gave the first smallpox inoculations in Boston following America's biggest outbreak.
Janet Parker became the last person to die of smallpox in Birmingham, United Kingdom.
The Boston Bicycle Club was formed, becoming the first cycling club in the United States.
American Academy of Arts & Science was established in Boston with James Bowdoin, John, and Samuel Adams as founding members.
Smallpox is officially declared eradicated.