The Boston Bicycle Club was formed, becoming the first cycling club in the United States.
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The Great Fire of Boston destroyed 349 buildings.
American Academy of Arts & Science was established in Boston with James Bowdoin, John, and Samuel Adams as founding members.
A medical paper on smallpox was published in Boston, making it the first medical publication in American history.
Telegraph wires linked new York and Boston.
Boston became the first American city to have a town meeting.
