Ether was used as an anesthetic for the first time, by American surgeon Crawford Long, in Athens, Georgia.
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The discovery of the chemical element Neptunium was announced.
The state of Georgia seceded from the United States of America.
The first documented blood transfusion took place using sheep blood in a teenage boy.
A Texan doctor performed the world's first successful partial skull and scalp transplant.
The first Atlanta International Pop Festival took place at Atlanta International Raceway in Hampton, Georgia, with as many as 150,000 partygoers.