The three ships carrying settlers who would later found Virginia, the first of the Thirteen Colonies, departed England.
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Virginia became the first state to ratify the Articles of Confederation.
Bacon's Rebellion set Jamestown, Virginia, on fire after a year of conflict to change Virginia's Native American-Frontier policy.
The first American test-tube baby, Elizabeth Jordan Carr, was born in Norfolk, Virginia.
The Battle of Bull Run took place at Manassas Junction, Virginia.
The United States Supreme Court declared that it was unlawful to discriminate in interstate travel.