The New Orleans Saints secured their first winning season after being in the NFL for 21 years.
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O.J. Simpson became the first NFL running back to rush for 2,000 yards in a season.
The Baltimore Colts NFL team relocated to Indianapolis, Indiana.
The Philadelphia Eagles beat the Green Bay Packers 34-29 in Brazil in the first NFL game in South America.
Carl Nassib became the first openly-gay NFL player to play a regular-season game.
The NFL started using the instant replay rule where video is analyzed to review what had just happened in a game.