The Polio epidemic took hold for the first time in the US at Rutland, Vermont.
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Jonas Salk's Polio vaccine tested by Jonas Salk was given final approval by the US Food and Drug Administration.
Isaac Fischer Jr. patented sandpaper in Springfield, Vermont, US.
Norwich University was founded in Vermont.
The first major mass trials of polio vaccines began.
The state of Vermont became the first to abolish adult slavery after declaring the Constitution of Vermont.