During the Black Death persecutions, 700 Jews were burned alive in their own homes in Basel, Netherlands.
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Thirty thousand lives were lost after a major earthquake shook Lisbon.
The world's first Jewish ghetto was established in Venice, Italy.
Jews in Germany over six years old were forced to wear the yellow star of David.
Pope Clement VI issued two papal bulls stating that Jews were not to blame for the Black Death.
Germany expels Polish Jews.