The first warrants were issued to arrest three women accused of witchcraft in Salem, Massachusetts, US.
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The Mayflower, filled with Puritan Pilgrims, spotted land at Cape Cod, Massachusetts.
Boston Light was illuminated for the first time.
Twelve doctors at Massachusetts General Hospital in Boston performed the first successful reattachment of a human limb – it was the severed arm of a boy.
There were sightings of a giant sea serpent in Gloucester, Massachusetts.
Massachusetts became the first US state to legalize same-sex marriage.
