The CERN Large Hadron Collider was powered up for the first time.
Chris Messina Tweeted #barcamp, which became the first use of a hashtag on Twitter.
Storm Botnet sent a staggering 57 million emails.
Bioshock, the first-person dystopian horror shooter game, was released for Xbox 360 and PC.
J.K. Rowling's final book in the series 'Harry Potter and the Deathly Hallows' book was published worldwide.
Erden Eruç began the world's first successful solo human-powered circumnavigation of the world.
The first-generation Apple iPhone went on sale.
Michael Bay's Transformers premiered in Sydney, Australia.
Rihanna released her third studio album titled 'Good Girl Gone Bad.'
The Coen brothers film, 'No Country for Old Men,' premiered at the Cannes Film Festival.
Pirates of the Caribbean: At World's End premiered in Anaheim, California.
Sicko, a documentary on the US healthcare system, premiered at the Cannes Film Festival.
Jazz composer and musician John Coltrane received the Special Citation Pulitzer Prize after his death.
Rolling Stones guitarist Keith Richards has confirmed that he did snort his father's ashes.
Rihanna's single 'Umbrella' was released.
The PlayStation 3 was released in Europe, Austrailia, New Zealand, Africa, and the Middle East.
The website Tumblr was launched by its founder David Karp.
American pop singer Ariana Grande joined YouTube at 13 years old.
Steve Jobs announced Apple's very first smartphone, the iPhone 1.
The Madrid Barajas International Airport was bombed.
The Nintendo Wii was released in the US.
Sony released the PlayStation 3 console in North America.
Al Jazeera English was launched.
The James Bond movie 'Casino Royale,' with Daniel Craig as Bond, premiered in London.
Google announced that it had acquired YouTube for $1.65 billion.
Julian Assange launched WikiLeaks.com.
Sacha Baron Cohen's mockumentary 'Borat' premiered at the Toronto International Film Festival.
Stephanie Myers published New Moon, the second novel in the Twilight series.
Two of Edvard Munch's stolen artworks were found after being missing for two years.
At just 30 years old, golf professional Tiger Woods won the 50th PGA, making him the youngest person ever to win a PGA.
Twitter was launched to the public.
British singer-songwriter Lily Allen released her first album, 'Alright, Still,' in the UK.
Pirates of the Caribbean: Dead Man's Chest premiered at Disneyland Resort, Anaheim, California.
The Apple MacBook was released.
The first-ever Tweet was published on Twitter.
Walt Disney announced it was going to buy Pixar.
Brokeback Mountain film was released, directed by Ang Lee, and based on the story by Annie Proulx.
RedOctane released Guitar Hero for PlayStation 2 in North America.
The fourth movie of J.K. Rowling's novel series, 'Harry Potter and the Goblet of Fire,' premiered in Leicester Square, London, UK.
Sid Meier's Civilization IV was made available to PC players in North America.
Stephenie Meyer's vampire novel 'Twilight' was published.
The Danish newspaper Jyllands-Posten published a controversial cartoon of the Prophet Muhammad.
The pilot episode of 'Supernatural,' created by Eric Kripke, aired on The WB Television Network.
American romantic-comedy Wedding Crashers premiered.
Reddit was founded in Medford, Massachusetts.
David Tennant was seen for the first time on Doctor Who.
The Huffington Post was launched, founded by Arianna Huffington, Andrew Breitbart, Kenneth Lerer, and Jonah Peretti.
The Airbus A380 passenger airliner successfully underwent its maiden flight.
The first video was uploaded to YouTube.
ABC debuted the first season of 'Grey's Anatomy.'
