The first railway line in Pakistan opened, with trains running from Karachi to Kotri.
London launched its first tram, built by George Francis Train from NYC.
Inventor Elisha Otis acquired a patent for a steam engine for elevators.
At 11 years old, Grace Bedell wrote to Abraham Lincoln, saying he should grow a beard.
The world's first recording of the human voice is created.
English Novelist George Eliot completed her famous book called 'The Mill on the Floss.'
Charles Darwin published his revolutionary work, On the Origin of Species.
Charles Blondin became the first person to cross Niagara Falls by walking across a tightrope.
The Codex Sinaiticus – one of the oldest known copies of the bible – was discovered in Egypt.
Inventor Hamilton Smith received his patent for his rotary washing machine.
Hyman Lipman patented the pencil with an eraser on top.
The National Association of Baseball Players was established in New York.
Alfred Tennyson's poem 'Charge of the Light Brigade' was published in 'The Examiner.'
Henry David Thoreau Publishes Walden.
Harriet Beecher Stowe publishes her novel Uncle Tom's Cabin.
Herman Melville's novel 'Moby Dick' was published by Harper & Brothers in New York.
Inventor Alan Clark was granted his patent for the telescope.
Moby Dick is published for the first time
The First America's Cup is held.
Isaac Singer was granted his patent for a commercial sewing machine.
Uncle Tom's Cabin, an anti-slavery novel by Harriet Beecher, was first published.
The world's first chess tournament is held in London.
Giuseppe Verdi's opera, Rigoletto, receives its premiere.
Harriet Tubman escaped from slavery.
Author Edgar Allan Poe was last seen alive. He was disorientated, lying in a gutter in Baltimore, Maryland, US.
Abraham Lincoln received a patent for a device that would lift a boat over shoals and obstructions.
Walter Hunt patented the safety pin.
The first WHSmith railway bookstore opened at London Euston Railway Station, London, UK.
Karl Marx and Friedrich Engels publish 'The Communist Manifesto'.
The English writer Charlotte Bronte's novel 'Jane Eyre' was published by Smith, Elder & Co.
Felix Mendelssohn's Wedding March is used at a wedding for the first time.
Inventor Elias Howe was awarded the patent for the lockstitch sewing machine.
The saxophone is patented.
Baltimore and Philadelphia were linked up by telegraph.
First Issue of Scientific American hits the newsstands.
Felix Mendelssohn's Violin Concerto is premiered.
A glass treasure vase that dated back to between 1 – 25 AD was smashed by a drunk man.
The New York Evening Mirror published Edgar Allan Poe's famous poem 'The Raven.'
The first telegraph message was sent.
A Christmas Carol by English author Charles Dickens was published.
Micah Rugg patented a machine for dressing bolt heads.
The Vienna Philharmonic Orchestra performed its first concert.
The first sewing machine was patented in the US.
Charles Dickens and his wife arrived in Boston, US, from Liverpool, UK.
British Novelist Charles Dickens and his wife Catherine left England for America on board the Britannia ship.
The first wagon train arrived in California after having left Independence, Missouri, in May 1841.
John Hampton patented the Venetian blind.
Samuel Morse was granted the patents for his telegraph.
Ephraim Morris patented the car brake for railroads.
Samuel Morse presents the telegraph to the public.