English Protestant author William Tyndale published 'The Obedience of a Christian Man' in Antwerp, Belgium.
Michelangelo's Sistine Chapel ceiling mural was presented to the public.
Michelangelo began his three-year project sculpting the Statue of David.
The 15th-century Breton-French-Latin dictionary called the Catholicon was published.
Michelangelo was commissioned to create his sculpture Pietà.
Leonardo da Vinci unsuccessfully tried to fly his famous Flying Machine invention for the first time.
Mainz Psalter was published, making it the first book with a printed publication date on it.
The first printing of the Gutenberg Bible was completed.
All local Jews had to submit their books through King James I to be investigated.
