The pocket watch patent was awarded to Dutch mathematician and scientist Christiaan Huygens.
John Dryden was appointed as England's first Poet Laureate by King Charles II.
The US held its first horse race in Long Island, New York.
Nicolaus Copernicus' revolutionary book De revolutionibus orbium coelestium is banned by the Catholic Church.
Shakespeare's Sonnets were first published in London.
The world's first opera is premiered.
Miguel de Cervantes published his novel Don Quixote.
The Bodleian Library, situated at The University of Oxford, England, opened its doors to the public.
The first printed edition of the Zohar (Jewish kabbalah) was published.
The Church of England adopted the Book of Common Prayer.
After over four years in the making, Michelangelo unveiled 'The Last Judgment' painting at the Sistine Chapel, Vatican City.
The first complete English Bible translation was published.
English Protestant author William Tyndale published 'The Obedience of a Christian Man' in Antwerp, Belgium.
Michelangelo's Sistine Chapel ceiling mural was presented to the public.
Michelangelo began his three-year project sculpting the Statue of David.
The 15th-century Breton-French-Latin dictionary called the Catholicon was published.
Michelangelo was commissioned to create his sculpture Pietà.
Leonardo da Vinci unsuccessfully tried to fly his famous Flying Machine invention for the first time.
Mainz Psalter was published, making it the first book with a printed publication date on it.
The first printing of the Gutenberg Bible was completed.
The Gutenberg Bible is published.
All local Jews had to submit their books through King James I to be investigated.
The earliest surviving dated printed book is produced in China.